Globin Chains by a Murine Monoclonal Antibody
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چکیده
Human embryonic e globin chains were isolated from lysates of cultured human leukemic K562 cells induced with hemin. Mice were immunized with globin chains, and a murine hybridoma cell line was established that secreted monoclonal anti-c globin antibody. A sensitive and specific slot blot immunoassay for e globin chains has been developed. #{128} Globin chains were shown to be present in hemolysates from fetuses of 20 weeks’ gestation but were not
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تاریخ انتشار 2005